Dr. David M. Eddy's Reply: Chest X-rays

Preoperative chest x-rays: a teachable moment.

MrX,aman inhismid50swithahistoryofmild intermittent asthma and an increasingly painful umbilical hernia, presented to a general surgery clinic for a preoperative evaluation.Basic laboratorytest resultsandcardiopulmonary examination findings were normal, and a reducible hernia was noted. A chest radiograph (CXR) was obtainedfortheindicationofpreoperativeevaluationinapatient with asthma older tha...

Diagnostic Utility of Chest X-rays in Neonatal Respiratory Distress: Determining the Sensitivity and Specificity

Background: Chest radiography is one of the most usual diagnostic tools for respiratory distress. Objective: The purpose of this study is to assess the specificity, sensitivity and clinical value of chest radiography of neonates with respiratory distress.Patients and Methods: A descriptive- analytical study was conducted on 102 neonates that were in neonatal intensive care unit of Imam Reza and...

Dr. David Rimm

Dr. David Rimm, MD PhD, is a professor of Pathology at the Yale University School of Medicine specializing in developing quantitative, diagnostic techniques. His lab recently engineered a fluorescence-based algorithm, Automated Quantitative Analysis (AQUA), to analyze tissue microarrays in the hope of moving toward personalized medicine and diagnoses.

Dr. Wallace and Dr. Stone reply.

Reply to Dr. Weiskirchen.

TO THE EDITOR: We would like to thank Dr. Weiskirchen (5) for his interest in our recent publication (3). As we mentioned in the DISCUSSION and as pointed out by Dr. Weiskirchen, the absence of protein data in our adenovirus model represents a limitation of our study. Regarding the RNA expression, we also expected to find a greater difference in ccn1/cyr61 gene expression in the mice instilled ...